BACKGROUND: Among birth defects, cleft palate is one of the most common defects universally, with a prevalence rate of 1 in 700 live-born children. PURPOSE: To investigate the relationship between emotional and social concern and caring for a child with a cleft palate, with a particular focus on the various emotional and social dimensions and concerns in Jordan. METHOD: A cross-sectional correlational study was conducted at one specialized Cleft Palate Unit using convenience sample of 312 mothers of children with and without cleft palate. RESULTS: Analysis revealed that there was a significant difference (t = 2.918, p = 0.004) in the presence of anxious feelings between mothers with CP children and those without CP children. there was a significant difference between mothers in different age groups (F = 3.302, p = 0.011) in their problems with social support and their worrier's regarding their child's future (F = 3.670, p = 0.006). Also, the analysis revealed that mothers' education level contributed to differences in their feelings of sadness (F = 4.330, p 0.002), isolation feelings (F = 4.543, p = 0.001), their problems with social support (F = 6.729, p < 0.001), and their worrier's regarding their child's future (F = 3.350, p = 0.011).CONCLUSION: Mothers of children with cleft palate face various emotional and social challenges while caring for their children. Identifying and addressing the emotional and social concerns of caring for children with cleft palate is crucial. Healthcare providers and policymakers should ensure that mothers of children with cleft palate receive the necessary support to help them and their children across this long journey.